Keyboard Buttons
There's a little bit of an oddity about Resident Evil 4. It doesn't change from button prompts if you're not using a controller, which can be pretty annoying. If you're dead set on using a keyboard, this will lend a hand, allowing you to see button prompts for actions when events occur that call for them.
Hunk replacement for Leon (Story mode)
Leon's a pretty tough guy, but no character in the Resident Evil universe is as coldly calculating and determined as Hunk. So why not steal him away from Umbrella for a bit to go hunt down the president's daughter and kill some B.O.W.s? This mod will swap Leon with Hunk's model in the story mode, allowing you to play through the whole game as this legendary operative.
Michael Jackson Skin
Replacement texture for Mafia Leon by Leon_me_kennedy1438.
Ada Wong Goth Chick Clothes Pack
This mod makes Ada Wong look Gothic.
MP40
The Chicago Typewriter (tommy gun) is a pretty potent and powerful weapon, but it's not the only iconic sub machine gun in history. This one repaints the Chicago Typewriter with another iconic weapon out of its own time. This German MP40 was the Tommy Gun's counterpart and will serve you just as well as it's American counterpart.
Enhanced Environment Part 1
This mod changes overhauls the textures in-game.